研究员、博士生导师

基本情况

出生年月：1970.06

最高学位：工学博士

工作单位：武汉理工大学，新材料研究所

工作地址：湖北省武汉市洪山区武汉理工大学（马房山校区）新材料研究所

联系电话：027-87884448

Email: daihonglian@whut.edu.cn

教育及工作经历

2002.3-2005.6  武汉理工大学，材料学专业，工学博士

1997.9-2000.6  武汉理工大学，生物医学工程专业，工学硕士

1989.9-1993.6  武汉工业大学，材料科学专业，工学学士

2007.12-至今   武汉理工大学材料复合新技术国家重点实验室，研究员

2006.12-2007.12  荷兰格罗宁根大学访问研究员

2002.10-2007.11  武汉理工大学生物材料与工程研究中心，副研究员

2002. 3-2002. 6   香港科技大学访问学者

1998.10-2002.9   武汉理工大学生物材料与工程研究中心，助理研究员

1993. 7-1998.9   武汉工业大学生物材料与工程研究中心，实习助理研究员

学术兼职

戴红莲兼任中国生物材料学会常务理事、中国生物材料学会神经修复材料分会副主任委员、中国生物材料学会青年委员会、骨修复材料与器械分会、再生材料委员会委员，武汉理工大学·嘉一高科3D硬组织修复材料工程技术研究中心主任，Journal of Wuhan University of Technology: Materials Science Edition编委、《中国神经再生研究（英文版）》（NRR）杂志中国区域中青年编委等。

研究领域及主要成果

1.生物材料及医疗器械的设计与研发

2. 生物超材料与智能器件

3.生物3D打印、类器官与再生医学

4.药物控释系统

主持科研项目

1. 国家自然科学基金面上项目：双场驱动仿生梯度释药支架多线索调节神经-骨代谢研究

2. 国家自然科学基金面上项目：磁性长效多药缓释型骨修复材料的构建及其成骨机制

3. 国家自然科学基金面上项目：磁靶向性形状记忆复合微球的血管栓塞机制

4. 国家重点研发计划课题：多种陶瓷材料的光固化增材连续成形机理、精度保障与光散射调控技术

5. 国家重点研发计划课题：诱导型纳米复合材料神经移植物研发

6. 湖北省技术创新计划项目：生物活性硬组织粘合修复材料关键技术及产品研发

7. 湖北省技术创新专项重大项目：生物活性椎体增强材料关键技术研究

8. 湖北省科技支撑计划：空心铁氧体/体温形状记忆聚氨酯功能型血管栓塞纳米复合材料的研发

9. 广东省基础与应用基础研究基金区域联合基金重点项目：大尺寸高质量立体光刻陶瓷的高效成型及缺陷控制机理研究

10. 深圳市基础研究重点项目：三维打印构建高强度可降解天然有机-无机复合仿生骨再生支架研究

获奖情况

代表性论文、专著和专利等（不超过10项）

1. Yuanfang Hou, Xinyi Tan, Xianzhen Dong, Xinyue Liang, Kun Liu, Hao Zhang, Zhiqiang Li, Junwei Yang, Zixuan Pang, Yawei Yao, Aixi Yu*, Honglian Dai*. Photo-responsive H2S composite system regulates the nerve regeneration microenvironment through multiple pathway. Advanced Materials, 2025, 2413992

2. Yanan Zhao, Jiawei Liu, Liangcong Hu, Xiaokang Yao, Rong Tu, Takashi Goto, Lianmeng Zhang, Xiaopei Wu*, Guohui Liu*, Honglian Dai*. Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion. Biomaterials, 2025, 320: 123191.

3. Wei Wu, Yuhao Xia, Ye Huang, Wenying Wei, Xiaopei Wu, Rong Tu*, Tian Wu*, Honglian Dai*. Magnetron sputtering dual-ion sequential release coating on PET artificial ligament promotes vascular nerve regeneration and graft-bone integration. Advanced Functional Materials, 2024, 34(51)：2410389.

4. Chuhang Hong, Xiaopei Wu, Youfa Wang, Jian Huang*, Honglian Dai*. Biomimetic fusion: platyper's dual vision for predicting protein-surface interactions. Materials Horizons, 2024, 11（15）：3528-3538.

5. Liupan Xu, Haifei Kang, Wenying Wei, Takashi Goto, Xiaopei Wu, Honglian Dai*. Freezing, salting-out and mineralization-a simple, universal and modular strategy for constructing mineralized hydrogels. Advanced Functional Materials, 2024, 34(41): 2406367.

6. Wen Hou, Jiawei Liu, Wenying Wei, Yanan Zhao, Xiaopei Wu*, Honglian Dai*. All-in-one strategy to develop a near infrared-triggered multifunctional bioactive magnesium phosphate bone cement for bone repair. Acta Biomaterialia, 2024, 182: 111-125.

7. Chenxi Lian, Jiawei Liu, Wenying Wei, Xiaopei Wu, Takashi Goto, Haiwen Li, Rong Tu*, Honglian Dai*. Mg-gallate metal-organic framework-based sprayable hydrogel for continuously regulating oxidative stress microenvironment and promoting neurovascular network reconstruction in diabetic wounds. Bioactive Materials, 2024, 38: 181-194.

8. Yue Wang, Kun Liu, Wenying Wei, Honglian Dai*. A multifunctional hydrogel with photothermal antibacterial and antioxidant activity for smart monitoring and promotion of diabetic wound healing. Advanced Functional Materials, 2024, 34(38): 2402531.

9. Xianzhen Dong, Hao Zhang, Ping Duan, Kun Liu, Yifeng Yu, Wenying Wei, Weixing Wang, Yuhang Liu, Qiang Cheng, Xinyue Liang, Yuanfang Huo, Lesan Yan, Aixi Yu*, Honglian Dai*. An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment. Science Advances, 2023, 9(51): eadi1078.

10. Yanan Zhao, Liangcong Hu, Honglian Dai*, Pengzhen Zhuang, Kai Huang, Wen Hou, Jiawei Liu, Tong Tu, Takashi Goto. Smart trap-capture-kill antibacterial system for infected microenvironment improvement and vascularized bone regeneration via magnetic thermotherapy. Advanced Functional Materials, 2023, 2214734.

11. Jiawei Liu, Wen Hou, Wenying Wei, Jian Peng, Xiaopei Wu, Chenxi Lian, Yanan Zhao, Rong Tu, Takashi Goto, Honglian Dai*. Design and fabrication of high-performance self-setting trimagnesium phosphate. Bioactive Materials, 2023, 28: 348-357.

12. Yuhao Xia, Xirui Jing, Xiaopei Wu, Pengzhen Zhuang, Xiaodong Guo*, Honglian Dai*. 3D-printed dual-ion chronological release functional platform reconstructs neuro-vascularization network for critical-sized bone defect regeneration. Chemical Engineering Journal, 2023, 465: 143015.

13. Kai Huang, Wenbin Liu, Wenying Wei, Yanan Zhao, Pengzhen Zhuang, Xiaoxuan Wang, Youfa Wang, Yihe Hu, Honglian Dai*. Photothermal hydrogel encapsulating intelligently bacteria-capturing Bio-MOF for infectious wound healing. ACS Nano, 2022, 16(11):19491-19508.

14. Xianzhen Dong, Ping Wu, Lesan Yan, Kun Liu, Wenying Wei, Cheng Qiang, Xinyue Liang, Yun Chen*, Honglian Dai*. Oriented nanofibrous P(MMD-co-LA)/Deferoxamine nerve scaffold facilitates peripheral nerve regeneration by regulating macrophage phenotype and revascularization. Biomaterials, 2022, 280: 121288.

15. Wenying Wei, Honglian Dai*. Articular cartilage and osteochondral tissue engineering techniques: recent advances and challenges. Bioactive Materials, 2021, 6: 4830-4855.