Prof. Yingchao Han
Address:7th floor, YIFU Building, Wuhan University of Technology
Email：firstname.lastname@example.org Tel: 18986218516
RESEARCH AREA AND INTERESTS
1. Bioceramic and biomedical inorganic nanomaterials
1.1 Fabrication of hydroxyapatite (HAP) powders and bioceramics;
1.2 Adsorption properties of HAP nanoparticles to biomolecules (such as serum albumin, heparin and salic acid) and the interaction of HAP nanoparticles with cells;
1.3 Preparation and application of rare earth doped HAP nanoparticles as bioimaging agent.
1.4 Application of HAP nanoparticles as drug or gene carriers
2. Organic/inorganic nanocomposite for biomedical application
2.1 Fabrication of nanocomposites of polymers and nano calcium phosphate.
2.2 Application of biomedical composites for tissue regeneration
3. Drug delivery nano-carrier system and drug formulation
3.1 Preparation of anti-cancer drug loading amphiphilic block micelles formulation;
3.2 Synergistic effects study between multiple anti-cancer drugs
1996.09-2000.06, Bachelor Degree, Wuhan University of Technology, China
2000.09-2002.06, Master Degree, Wuhan University of Technology, China
2004.09-2007.12, Doctor Degree, Wuhan University of Technology, China
2002.07-2004.10, Researcher Assistant, Wuhan University of Technology, China
2004.11-2009.08, Assistant Researcher, Wuhan University of Technology, China
2009.09-2017.08, Associate Researcher, Wuhan University of Technology, China
2010.06-2012.06, Postdoctoral Researcher, University of Nebraska Medical Center, USA
2017.09-present, Researcher, Wuhan University of Technology, China
(1) National Key R & D Projects, Ministry of Science and Technology: Study of biomedical materials for additive manufacturing of bone and joint personalized prosthesis;
(2) National Natural Science Foundation of China, General Program: Luminescence synergistic enhancement and in vivo metabolism of rare earth doped nano apatite as tumor imaging agent；
(3) Science and Technology Partnership Program, Ministry of Science and Technology of China: Collaborative technology research and demonstration of biodegradable organic-inorganic nanocomposite biomedical membrane；
Dong Yan, Bin Zeng, Yingchao Han, Honglian Dai, Jie Liu, Yunlong Sun, Feng Li. Preparation and laser powder bed fusion of composite microspheres consisting of poly(lactic acid) and nano-hydroxyapatite. Additive Manufacturing, 2020, 34:101305.
H. M. C. Suboda Wijerathne, Dong Yan, Bin Zeng, Yanping Xie, Hongchao Hu, M. Nirmali Wickramaratne, Yingchao Han. Effect of nano‑hydroxyapatite on protein adsorption and cell adhesion of poly(lactic acid)/nano‑hydroxyapatite composite microspheres. SN Applied Sciences, 2020, 2:722.
Xiaojun Zhang, Qingguo Xing, Lixuan Liao and Yingchao Han. Effect of the Fluorine Substitution for –OH Group on the Luminescence Property of Eu3+ Doped Hydroxyapatite. Crystals 2020, 10: 191.
Hongyan Bi, Tianyi Feng, Binbin Li, Yingchao Han. In Vitro and In Vivo Comparison Study of Electrospun PLA and PLA/PVA/SA Fiber Membranes for Wound Healing. Polymers, 2020, 12: 839.
Qingguo Xing, Xiaojun Zhang, Dulan Wu, Yingchao Han, M. Nirmali Wickramaratne, Honglian Dai, Xinyu Wang. Ultrasound-Assisted Synthesis and Characterization of Heparin-Coated Eu3+
Doped Hydroxyapatite Luminescent Nanoparticles. Colloid and Interface Science Communications 29 (2019) 17–25
Peilong Ni, Hongyan Bi, Gang Zhao, Yingchao Han, M. Nirmali Wickramaratne, Honglian Dai, Xinyu Wang. Electrospun preparation and biological properties in vitro of polyvinyl alcohol/sodium alginate/nano-hydroxyapatite composite fiber membrane. Colloids and Surfaces B: Biointerfaces 173 (2019) 171–177
Dong Yan, Yuxin Lou, Yingchao Han, M. Nirmali Wickramaratne, Honglian Dai, Xinyu Wang. Controllable synthesis of poly(acrylic acid)-stabilized nanohydroxyapatite suspension by an ultrasound-assisted precipitation method. Materials Letters, 2018, 227:9–12
Yunfei Xie, Wangmei He, Fang Li, Thalagalage Shalika Harshani Perera, Lin Gan, Yingchao Han, Xinyu Wang, Shipu Li, Honglian Dai. Luminescence Enhanced Eu3+/Gd3+ Co-Doped Hydroxyapatite Nanocrystals as Imaging Agents In Vitro and In Vivo. ACS Applied Materials & Interfaces, 2016, 8 (16)：10212–10219.
Fang Li, Qingguo Xing, Yingchao Han, Yue Li, Wei Wang, Thalagalage Shalika Harshani Perera, Honglian Dai. Ultrasonically assisted preparation of poly(acrylic acid)/calcium phosphate hybrid nanogels as pH-responsive drug carriers. Materials Science and Engineering C, 2017, 80: 688-697
Wangmei He, Yunfei Xie, Qingguo Xing, Peilong Ni, Yingchao Han, Honglian Dai. Sol-gel synthesis of biocompatible Eu3+/Gd3+ co-doped calcium phosphate nanocrystals for cell bioimaging. Journal of Luminescence, 2017,192: 902–909