研究员、博士生导师

基本情况

出生年月：1977.04

最高学位：工学博士

工作单位：武汉理工大学新材料研究所/生物材料与工程研究中心

工作地址：武汉理工大学西院逸夫楼7楼

Email: hanyingchao@whut.edu.cn

教育及工作经历

2017.09-至今     武汉理工大学，新材料研究所/生物材料与工程研究中心，研究员

2009.09-2017.08    武汉理工大学，新材料研究所/生物材料与工程研究中心，副研究员

2010.06-2012.06    美国内布拉斯加大学医学中心，博士后

2004.11-2009.08    武汉理工大学，生物材料与工程研究中心，助理研究员

2002.07-2004.10    武汉理工大学，生物材料与工程研究中心，研究实习员

2005.03-2007.12    武汉理工大学，工学博士

2000.09-2002.07    武汉理工大学，工学硕士

1996.09-2000.07    武汉理工大学，本科

学术兼职

研究领域及主要成果

长期从事纳米生物材料，有机/无机复合医用材料，纳米药物可控释放系统领域。

主持科研项目

1. 科技部国家重点研发计划项目，2016YFB1101302，适用于骨与关节个性化植入假体增材制造生物医用材料的研制，2016/07-2020/06；

2.国家自然科学基金面上项目，51672206，稀土掺杂纳米磷灰石肿瘤显影剂的荧光协同增强与体内代谢，2017/01-2020/12；

3. 科技部国际科技合作项目，KY201602002，可降解有机－无机纳米复合医用药膜技术联合研究与示范，2016/12-2019/12；

4. 武汉市科技计划国际科技合作项目，2016030409020217，生物可降解聚乳酸/海藻酸钠/纳米磷酸钙复合医用药膜合作研究，2016/08-2018/08；

获奖情况

代表性论文、专著和专利等（不超过10项）

1. Fang Li, Qingguo Xing, Yingchao Han, Yue Li, Wei Wang, Thalagalage Shalika Harshani Perera, Honglian Dai. Ultrasonically assisted preparation of poly(acrylic acid)/calcium phosphate hybrid nanogels as pH-responsive drug carriers. Materials Science and Engineering C, 2017, 80: 688-697

2. Wangmei He, Yunfei Xie, Qingguo Xing, Peilong Ni, Yingchao Han, Honglian Dai. Sol-gel synthesis of biocompatible Eu3+/Gd3+ co-doped calcium phosphate nanocrystals for cell bioimaging. Journal of Luminescence, 2017,192: 902–909 (3) Jiali Guo, Yuting Mao, M. Nirmali Wickramaratne, Yingchao Han. Influence of alginate fixation on the adsorption capacity of hydroxyapatite anocrystals to Cu²⁺ ions. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2017, 529: 801-807

3. Yunfei Xie, Wangmei He, Fang Li, Thalagalage Shalika Harshani Perera, Lin Gan, Yingchao Han^*, Xinyu Wang, Shipu Li, and Honglian Dai^*. Luminescence Enhanced Eu³⁺/Gd³⁺ Co-Doped Hydroxyapatite Nanocrystals as Imaging Agents In Vitro and In Vivo. ACS Applied Materials & Interfaces, 2016, 8 (16): 10212–10219.

4. Yunfei Xie, Thalagalage Shalika Harshani Perera, Fang Li, Yingchao Han^*, Meizhen Yin^*. Quantitative Detection Method of Hydroxyapatite Nanoparticles Based on Eu³⁺ Fluorescent Labeling in Vitro and in Vivo. ACS Applied Materials & Interfaces, 2015, 7 (43): 23819-23823.

5. Yingchao Han, Xinyu Wang, Honglian Dai, Shipu Li. Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions. ACS Applied Materials & Interfaces, 2012, 4(9): 4616-4622.

6. Yingchao Han, Shipu Li, Xianying Cao, Lin Yuan, Youfa Wang, Yixia Yin, Tong Qiu, Honglian Dai, Xinyu Wang. Different Inhibitory Effect and Mechanism of Hydroxyapatite Nanoparticles on Normal Cells and Cancer Cells In Vitro and In Vivo. Scientific Reports, 2014, 4: 7134.

7. Xiaofei Lu, Yunfei Xie, Yingchao Han^*, Xinyu Wang, Honglian Dai, Shipu Li. Ultrasound-induced albumin gelation method for the preparation of nanostructured hydroxyapatite. Materials Letters, 2015, 161: 128-131.

8. Yingchao Han, Xinyu Wang, Honglian Dai, Shipu Li. Synthesis and luminescence of Eu³⁺ doped hydroxyapatite nanocrystallines: Effects of calcinations and Eu³⁺ content. Journal of Luminescence, 2013, 135: 281-287.

9. Yingchao Han^†, Zhijian He^†, Anita Schulz, Tatiana K. Bronich, Rainer Jordan, Robert Luxenhofer, Alexander V. Kabanov. Synergistic Combinations of Multiple Chemotherapeutic Agents in High Capacity Poly(2-oxazoline) Micelles. Molecular Pharmaceutics, 2012, 9(8): 2302-2313.

10. Thalagalage Shalika Harshani Perera, Yingchao Han^*, Xiaofei Lu, Xinyu Wang, Honglian Dai, Shipu Li. Rare Earth Doped Apatite Nanomaterials for Biological Application. Journal of Nanomaterials, 2015, 2015: 705390